Grace L. Guo and Wen Xie. Metformin action through the microbiome and bile acids. Nat Med. 24: 1789-1790 (2018) PMID: 30523325.
SUMMARY: Metformin functions through a gut microbiome-bile acid-farnesoid X receptor axis to lower glucose in type 2 diabetes, revealing a new therapeutic target in this disease.
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