PLRC researcher Dr David Geller, MD. along with Dr. Alex Soto-Gutierrez, MD., PhD. was awarded a five year R24 grant from the NIDDK for the Human Liver Tissue & Hepatocytes Research Resource (HLTHRR). “Our overall goal is to be a core lab which provides normal human liver tissue and normal human hepatocytes (HC) and non-parenchymal cells (NPC) including NPC sub-fractions (Kupffer cells, sinusoidal endothelial cells, cholangiocytes, and stellate cells) to biomedical researchers across the USA.”
For the past two years (2022-2024), the NIDDK has funded the Human HC Isolation and Distribution (HHID) in Dr. Geller’s lab at Pitt with bridge funding as a supplement to our active University of Pittsburgh P30 DK120531 “Pittsburgh Liver Research Center” (PI-Dr. S. Monga) which has allowed us to maintain the current human HC core lab for the USA. Previously, Dr Geller’s lab was part of the Liver Cell Tissue Distribution System (LTCDS) and Dr. Soto-Gutierrez’s lab isolates and distributes liver cells from diseased livers as a service of the Human Synthetic Liver Biology Core. Cumulatively we have over 25 years of experience isolating human HC with tremendous success and providing them to Pls around the country as the core NIDDK-funded lab in the USA.
Congratulations on securing funding for a much needed and invaluable resource in the liver research community!
