PLRC members have identified the following resources in their clinics and labs, which may be useful to other PLRC members. If you would like to use a resource listed below, please contact the investigator listed next to the resource.
Cell Lines
Hep3B | Kari Nejak-Bowen |
HepG2 | Kari Nejak-Bowen |
AML12 | Kari Nejak-Bowen |
primary mouse hepatocytes | Kari Nejak-Bowen |
Raw264.7 | Kari Nejak-Bowen |
sm-cc (mouse-derived immortalized cholangiocytes) | Kari Nejak-Bowen |
Animal Models
Mouse models
ATPIF1 knockout | Michael Jurczak |
ATPIF1fl/fl | Michael Jurczak |
Cre recominase under an alpha feto protein enhancer driven albumin promoter (Afp/Alb) | Wendy Mars, in collaboration with George Michalopoulos |
Fah-KO (C57BL/6 background) | Andrew Duncan |
FRGN (Fah-KO, Rag2-KO, Interleukin-2 common gamma chain-KO, NOD background) | Andrew Duncan |
Glypican transgenic under an albumin promoter | Wendy Mars, in collaboration with George Michalopoulos |
HGF flox crossed with a cre recombinase under an inducible tamoxifen promoter | Wendy Mars, in collaboration with George Michalopoulos |
HGF transgenic under a GFAP promoter | Wendy Mars, in collaboration with George Michalopoulos |
Integrin Linked Kinase (ILK) flox | Wendy Mars, in collaboration with George Michalopoulos |
Kindlin 2 flox crossed with the Afp/Alb cre recombinase | Wendy Mars, in collaboration with Cary Wu |
LRP1 flox crossed with the Afp/Alb cre recominase | Wendy Mars, in collaboration with George Michalopoulos |
Lymphocyte Specific Protein 1 (LSP1) knockout | Wendy Mars, in collaboration with George Michalopoulos |
LSP1 transgenic under an albumin promoter | Wendy Mars, in collaboration with George Michalopoulos |
Mdr2 KO (FVB background) | Kari Nejak-Bowen |
Mdr2 KO (C57Bl/6 background) tamoxifen inducible Sox9-Cre | Kari Nejak-Bowen |
MET flox crossed with a cre recombinase under an inducible tamoxifen promoter | Wendy Mars, in collaboration with George Michalopoulos |
MET flox crossed with the Afp/Alb cre recominase | Wendy Mars, in collaboration with George Michalopoulos |
MET flox crossed with a lysZ cre recominase | Wendy Mars, in collaboration with George Michalopoulos |
Mito-Keima (mitophagy reporter line) | Michael Jurczak |
PARK2flfl/Albcre+/- | Michael Jurczak |
PARK2flfl/Vilcre+/- | Michael Jurczak |
PARK2 knockout | Michael Jurczak |
S45D β-catenin-mutated mice (C57Bl/6 background) | Kari Nejak-Bowen |
u-PA knockout | Wendy Mars, in collaboration with George Michalopoulos |
u-PA receptor knockout | Wendy Mars, in collaboration with George Michalopoulos |
Rat models
DPPIV+ F344 | Michael Oertel |
DPPIV- F344 | Michael Oertel |