Liver-Related Work

I have been working in the Dept. of Surgery for more than 15 years. My research interests include computational and systems biology approaches to inflammation in multiple disease states (sepsis/trauma, liver diseases, wound healing, chronic inflammatory diseases, and cancer), coupled to biochemical, cellular, animal, and clinical studies.

Ongoing Research Studies: 

• Collaboration with Drs. Timothy Billiar and Yoram Vodovotz (Dept. of Surgery) to study the role of toll-like receptors in isolated hepatocytes and animal models of LPS-induced inflammation.
• Collaboration with Drs. Robert Squires (Dept. of Pediatrics) and Yoram Vodovotz on systems biology approaches to help decipher the inflammatory complexity of Pediatric Acute Liver Failure (PALF).
• Collaboration with Dr. Paulo Fontes (Dept. of Surgery) aimed at defining novel inflammatory pathways associated with a novel extracorporeal perfusion system for liver transplantation.
• Collaboration with Dr. Vijay Gorantla (Dept. of Plastic Surgery) on systems biology approaches to experimental models of vascularized composite allotransplantation (VCA).
• Collaboration with Dr. Jorg Gerlach (Depts. of Surgery and Bioengineering) on a hepatocyte-based biohybrid device for adaptive control of inflammation.

Research Professor of Surgery