Rodrigo Machado-Florentino, PhD

BST S420
200 Lothrop St
Pittsburgh PA 15213

Liver-Related Work

Recently some point mutations have been associated with specific liver diseases. My interested is to understand the relationship between these mutations and the incidence of liver disease to find out the mechanism behind it. With the advances in induced pluripotent stem cell (iPS cell) technology and the ability to differentiate these cells into hepatic cells, such as hepatocytes, cholangiocytes and stellate cells, a new and a better model is available to study human liver diseases.

Selected Publications:

View Dr. Florentino’s publications on PubMed


Working with Dr. Alejandro Soto-Gutierrez, Dr. Alina Ostrowska, Dr. Andrew Feranchak, Dr. James Squires and recently with Dr. Lans Taylor team at the University of Pittsburgh Drug Discovery Institute.

Human induced plurypotent stem cells (hiPSC), gene editing, genotyping, and liver reperfusion.

Postdoctoral Associate
Department of Pathology