Nicholas (Nick) Khoo, PhD
200 Lothrop St
Pittsburgh, PA 15261
My research has largely focused on the mechanisms by which bioactive lipids, particularly those derived from the oxidative inflammatory reactions of nitric oxide called nitro-fatty acids, prevent the pathogenesis of obesity-related metabolic diseases. Currently, we are exploring the mechanistic role of hyperuricemia in fructose-driven NAFLD and the progression to NASH by targeting enzymes responsible for uric acid production pharmacologically as well as using novel gain- and loss-of-function approaches with genetic mice.
View Dr. Khoo’s publications on PubMed
w/ Drs. Arteel, Jurczak and Schopfer