Clinical and Research Interests: Dr. Ostrowska’s clinical interest is focused on providing substantial scientific and technical input and expertise in all aspects of primary human hepatocyte isolation, culture and transplantation. She is currently working on the development of an independent research program to investigate mechanisms of primary hepatocyte cryobiology and cold preservation. She is also interested in the characterization of human hepatocytes isolated from non-transplantable livers, including evaluation of CYP450s activities in cells isolated from explanted cirrhotic liver specimens obtained from patients undergoing OLT. Participation in clinical trial of hepatocyte transplantation.

There is a pressing need for alternative therapeutic methods effective in the treatment of patients with liver insufficiency. Isolated human hepatocytes may be a viable alternative or adjunct to orthotopic liver transplantation in such patients. Dr. Ostrowska is defining and managing both preclinical and clinical trial strategy, ensuring all activities adhere to cGMP policies, as well as FDA regulations, and IND guidelines.