Drs. Obaid Shaikh (Department of Medicine) and Takis Benos (Department of Systems & Computational Biology, and co-Director of PLRC’s GSBC) have been awarded a grant from Mallinckrodt Pharmaceuticals to study, “Predictive modeling of acute kidney injury-hepatorenal syndrome (AKI-HRS) among US veterans with cirrhosis.” The team is proposing to perform a case-control study of US veterans to determine factors associated with the development of AKI-HRS, and to develop and validate a predictive model of the syndrome. Additionally, they will employ machine learning tools to develop highly accurate adaptive algorithms and predictive models. The study will be performed with data acquired from the Veterans Affairs (VA) Corporate Data Warehouse (CDW), and the total award amount is $316,000 over two years. Their goal is that the application of a predictive model with a high level of accuracy will help improve resolution of AKI-HRS and overall survival. Congratulations to Dr. Shaikh and Dr. Benos! Helping to establish such multidisciplinary teams is one of the major goals of our PLRC.
