Bennewitz MF, Tutuncuoglu E, Gudapati S, Brzoska T, Watkins SC, Monga SP, Pradhan-Sundd T, Sundd P. P-selectin-deficient mice to study pathophysiology of sickle cell disease. Blood Adv. 2020 Jan 28;4(2):266-273. doi: 10.1182/bloodadvances.2019000603. PMID: 31968076; PMCID: PMC6988409.
ABSTRACT
P-selectin-deficient SCD mice are protected from lung vaso-occlusion.P-selectin-deficient SCD mice will be useful in assessing the benefits of anti-P-selectin therapy in diverse complications of SCD.
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