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Upcoming Events

Apr
9
Tue
PLRC Seminar Series: Dr. Jeff Albrecht @ S120 BST
Apr 9 @ 12:00 pm – 1:00 pm

George Michalopoulos Endowed Lectureship in the Department of Pathology at the University of Pittsburgh School of Medicine  

 

 

 

 

 

 

 

 

 

Jeffrey Albrecht, MD

Department of Medicine

Division of Gastroenterology, Hepatology, and Nutrition University of Minnesota    

Seminar title: Cyclin D1 at the nexus of cell cycle control and metabolism in the liver.

Biography: Jeffrey H. Albrecht MD is a gastroenterologist with a focus on hepatology (liver diseases). He was previously head of the Gastroenterology Division at Hennepin County Medical Center and director of the Liver Clinic at the Minneapolis VA Health Care System.

Research Summary

His research focuses on cell cycle control proteins in liver regeneration, metabolism, and carcinogenesis. In particular, his laboratory has investigated novel links between cyclin D1, hepatocyte metabolism, and fatty liver disease.

Clinical Summary

Dr. Albrecht’s clinical expertise is hepatology and general gastroenterology, including the diagnosis and treatment of liver diseases, cirrhosis, and liver cancer                                        

Apr
16
Tue
PLRC Seminar Series: Dr. Yulei Wang @ S120 BST
Apr 16 @ 12:00 pm – 1:00 pm

 

y.Wang picture

 

Yulei Wang, PhD
Senior Fellow/Group Leader
Department of Translational Medicine/Oncology
Genentech
South San Francisco, CA

 

 

Seminar title: Hepatocellular Carcinoma: Biomarker Discovery, Disease Biology, and Clinical Translation

Yulei joined Genentech in 2011. Currently a Senior Fellow/Group Leader in the Department of Translational Medicine, Yulei has extensive experiences in leading biomarker subteams for supporting both early stage (i.e. ADC/TDC and the TGFb franchise) and late stage clinical programs (i.e. cancer immunotherapies in hepatobiliary cancers). She also leads a group of biomarker scientists and oversees translational/reverse translational activities in GI disease area and across Morpheus signal-seeking combination platform.

As a well-recognized innovative scientific leader with a passion for both patients and science, Yulei has been a champion in leading the translation and reverse translation studies in liver cancer and ovarian cancer disease areas as well as global combination immunotherapy development. By integrating cancer genomics, digital pathology, ctDNA and single cell multi-omics in clinical biomarker studies, her team has successfully linked biomarker discovery, disease biology and clinical translation to enable transformative drug development.

In addition to leading clinical biomarker studies, Yulei is an accomplished postdoc mentor and head of translation research laboratory. Her group focuses on understanding the heterogeneity of the disease biology, tumor immune microenvironment and stroma biology to guide the development of novel therapeutic and diagnostic strategies.

 

                               

 

May
14
Tue
PLRC Seminar Series Dr. Lindsey Kennedy @ S120 BST
May 14 @ 12:00 pm – 1:00 pm

lindseykennedy

Lindsey Kennedy, PhD
Assistant Research Professor, Medicine
Indiana University School of Medicine

Seminar Title: “Multifunctional Roles for Endothelin Signaling in Models of Cholangitis

Host: Kari Nejak-Bowen, MBA, PhD

Dr. Lindsey Kennedy earned her Ph.D. in Medical Science from Texas A&M University in 2019. Following her doctoral studies, she began her post-doctoral fellowship in the Department of Gastroenterology and Hepatology at Indiana University School of Medicine. Noteworthy achievements during this phase include securing an Autoimmune Liver Disease Pilot Award from the AASLD Foundation
and obtaining the Career Development Award-2 from the VA. Dr. Kennedy is an ad hoc reviewer for multiple journals and serves as the Social Media Editor for Cellular and Molecular Gastroenterology and Hepatology. Her contributions extend to her roles on the AASLD Liver Fibrosis Committee and the Basic Science Research Committee. Presently, she holds dual positions as an Assistant Research Professor at Indiana University School of Medicine and a Health Science Specialist at the Richard L. Roudebush VA Medical Center. Dr. Kennedy’s research is centered on exploring cellularcrosstalk and signaling mediating cholestatic liver diseases. Her laboratory studies the role of estrogen in influencing sexually dimorphic outcomes in PBC and PSC, as well the intricate crosstalk between bile duct cells and endothelial cells facilitated by endothelin signaling, which she will be discussing today.

Highlights

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Dr. Mo Ebrahimkhani receives Ascending Star Award from SOM
March 25, 2024

Dr. Mo Ebrahimkhani, MD, a PLRC researcher who’s work combines synthetic biology and stem cell engineering to develop novel technologies... Read More

Dr. Mo Ebrahimkhani and colleagues publishes a new human embryo-like model in Nature
December 14, 2023

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Alex Soto-Gutierrez, Jai Behari, Lans Taylor and team publish in Gastro Hep Advances
October 24, 2023

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mycko-abstract
Ed Prochownik and team publish in Cell Reports
July 26, 2023

... Read More

George Michalopoulos, MD, PhD
Dr. George Michalopoulos adds to Pittsburgh’s rich Liver history
July 12, 2023

... Read More

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PLRC grant number P30 DK120531